Danis Stent Clinical Studies & Publications
NICE Medical technologies guidance Published: 31 March 2021: Danis stent for acute oesophageal variceal bleeding.
“Cost modelling shows that Danis stent is cost saving compared with balloon tamponade for acute oesophageal variceal bleeding being considered for definitive treatment. This is because having Danis stent results in a shorter stay in intensive care. To be cost saving, Danis stent needs to decrease intensive care stay by approximately 1 day or more compared with balloon tamponade.”
Expandable Oesophageal Stents Provide Safer Treatment of Oesophageal Variceal Bleeding: Presented at AASLD
64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
…28 patients were randomised to treatment using either a Sengstaken-Blakemore tube (n = 15, balloon tamponade) or an SX-Ella Danis expandable stent (n = 13) … Expandable oesophageal stents are superior to balloon tamponade in patients with cirrhosis who have uncontrolled, exsanguinating, oesophageal variceal bleeding … The better results are due to both a greater haemostatic effect and a lower rate of serious adverse events — especially of aspiration pneumonia — with the use of oesophageal stents…
Dechêne A, El Fouly AH, Bechmann LP, Jochum C, Saner FH, Gerken G, Canbay A.
…8 patients in whom endoscopic variceal ligation failed to control variceal hemorrhage were treated … The application of SEMS in esophageal hemorrhage showed a complete success in achieving hemostasis even after failed endoscopic variceal ligation…
Wright G, Lewis H, Hogan B, Burroughs A, Patch D, O‘Beirne J.
Gastrointest Endosc. 2010 Jan;71(1):71-8.
…10 patients with variceal hemorrhage with contraindications to TIPS insertion or BT … Stent insertion was successful in 9 of 10 patients … Insertion of the SX-Ella DANIS stent in patients with refractory variceal bleeding or complications of previous therapy is effective for the control of bleeding … In selected patients, SX-Ella DANIS stent insertion offers an alternative to other methods of salvage such as BT and TIPS and could be considered a substitute for BT after a prospective trial…